Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be fully reversed through standard nutritional support, resulting in deteriorating function. It may be masked by excess weight, obesity, edema, or tumor mass. Anorexia, which is a diminished appetite, is frequently observed in cancer patients, although its exact prevalence remains uncertain.
When cachexia primarily arises from reduced intake, it is termed cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, lipolysis, and decreased food intake, in contrast to straightforward cachexia.
Some researchers suggest that products from BC Weed Edible Canada could enhance appetite and alleviate nausea in cancer patients.
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Key Takeaways:
- THC capsules from BC Weed Edible Canada may assist cancer patients in consuming more and feeling less nauseous, thereby improving their overall quality of life.
- Studies indicate that edibles influence brain cells that regulate hunger, potentially aiding appetite issues in cancer patients and others.
- THC capsules provide accuracy, convenience, discretion, and long-lasting effects, making them ideal for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia signifies significant weight loss due to muscle and fat depletion, commonly observed in patients with advanced conditions such as heart failure, HIV/AIDS, COPD, kidney failure, and notably cancer.
This typically coincides with anorexia, which involves reduced appetite leading to at least a 5% decline in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS).
Hospitalized cancer patients often exhibit poor dietary intake, with nearly half being malnourished or at risk. Cachexia not only diminishes patients’ quality of life but also obstructs treatment and can hasten the end of life. Its prevalence escalates as death nears, with cachexia identified as the primary cause of death in over 20% of cases.
Despite its common occurrence, CACS frequently goes unnoticed and untreated in clinical environments due to the absence of clear definitions, diagnostic standards, classification systems, and approved therapies. Clinicians evaluate a patient’s nutritional status through various metrics such as body weight, skin fold thickness, and mid-arm circumference, yet body weight is often the primary focus, typically using inappropriate reference weights.
Treatment
The most apparent approach to address anorexia is to enhance nutrition; however, evidence supporting its effectiveness is limited. For cancer patients, nutritional care includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
Nonetheless, success varies based on cancer type and stage.
Pharmacological Approaches
Currently, there are no verified medications for treating Cancer Anorexia-Cachexia Syndrome (CACS), but some drugs are utilized off-label or are undergoing clinical trials. These medications can be categorized into four classes based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is used independently due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid from BC Weed Edible Canada could enhance the quality of life for cancer patients and pave the way for future treatments. This presents hope for cachexia patients, a condition where appetite diminishes and malnutrition ensues. It offers relief without intoxicating effects, positioning it as a potential remedy for these individuals.
Different edible formulations with varying effects are accessible, including inhaled THC for rapid onset and transient effects and orally ingested THC for slower absorption and prolonged effects. Sublingual administration provides quick onset with effects lasting 2 to 4 hours.
Clinical Trial
A study by researchers from Israel and the United States evaluated how edibles affect CACS in advanced cancer patients. This discovery significantly impacts the treatment of appetite disorders faced by cancer patients, individuals with anorexia, and potentially obesity.
Methods
They utilized edibles capsules containing two types of oil-based compounds. Participants were treated with 10 mg doses twice daily for six months, comprising 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants encountered side effects, the dose was lowered to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). Each doctor’s visit included participant weight checks. The primary goal was for participants to gain at least 10% more weight than their initial weight.
Results
Out of 24 patients who consented to participate, 17 began treatment with edibles. However, only 11 continued for more than two weeks. By the study’s conclusion, 3 out of 6 patients who completed the treatment met the primary goal of gaining at least 10% more weight. The weight of the remaining three patients remained unchanged.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Participants reported improved appetite and mood, along with reduced pain and fatigue.
Despite numerous challenges, this preliminary study demonstrated a 10% or greater weight gain in 3 out of 17 patients (17.6%) taking daily doses of 5 mg without significant side effects. These results support the need for a larger, more controlled investigation into edibles among CACS patients.
Cannabis Capsules
For those who prefer edibles, discovering new ways to enjoy products from BC Weed Edible Canada is always thrilling.
THC capsules represent one of the latest innovations in the edibles market. These capsules are edible pills containing a specific dose of THC, derived from a concentrated extract and a neutral oil. They are comparable to tinctures in capsule form (also referred to as oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract comes from the plant using a method selected by the manufacturer. THC capsules are abundant in THC, though some may exclusively contain CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble; hence, it is suspended in oil for effective absorption by the body. Common oils used include medium-chain triglycerides (MCT oils), which enhance digestion and absorption.
Benefits
Medical marijuana users and recreational consumers can gain advantages from edibles. They provide:
- Convenience: Consuming a capsule is as simple as any other oral supplement. Just take it with water, hassle-free.
- Precision Dosage: For medical users, precise control over cannabinoid intake is crucial for achieving desired effects. With THC capsules, each dose is pre-measured, eliminating uncertainty.
- Smoke-Free Option: Many individuals opt to avoid smoking or vaping for personal or health reasons. THC capsules present a smoke-free alternative, suitable for those with respiratory concerns.
- Longer Effects: Capsules generally provide extended effects compared to smoking or vaping, making them ideal for prolonged symptom relief over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
Place a Medical edibles Delivery Order Conveniently
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If you’re searching for flower, pre-rolls, edibles, or vape pens, you can easily explore BC Weed Edible Canada’s premium marijuana offerings sourced from the finest cannabis plants. Shop for your preferred THC products from the comfort of your home.
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Frequently Asked Questions
What are the different types of capsules?
One additional benefit of edibles capsules is their versatility – formulators can create diverse capsule types for consumers to select from. This ensures you can find capsules that align with your preferences.
- 1:1 Capsules: These capsules provide an equal ratio of THC to CBD in each dose, made with sativa or indica strains and available in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules offer a ratio of 3 parts CBD to 1 part THC in each dosage.
- THC Capsules: These capsules contain THC alone, with varying concentrations per capsule, crafted from different strains to produce specific effects.
- CBD Capsules: These consist solely of CBD, without THC, ensuring no mind-altering effects, designed for those seeking the benefits of CBD alone.
How do capsules interact with your body?
- The outer shell of the capsule dissolves in your digestive tract after consumption.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) undergo metabolism in the liver.
How long does it take for edibles effects to kick in?
Typically, THC capsules take around 90 minutes to start exhibiting effects, lasting 5 to 12 hours, gradually diminishing in intensity. Compared to inhaled cannabis, capsule effects generally last twice as long on average.
However, individual experiences may vary based on factors such as age, medications, personal tolerance, and cannabinoid composition. Some users may also experience differing effects due to the specific cannabinoids present, potentially influenced by the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, identify a trustworthy delivery service online that offers high-quality edibles. After selecting your products, opt for “order delivery,” and a delivery driver will safely deliver your order. Ensure the service is reputable for a smooth purchasing experience.
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